A case of diagnosis and treatment of Pasteurellosis

Chicken pasterellosis also known as chicken cholera, chicken hemorrhagic sepsis, commonly known as poultry defeat. It is an acute septic communicable disease caused by Pasteurella.
Not long ago, two small chicken farms in Meitang Town, Puning City had an acute epidemic characterized by diarrhoea, high fever and dyspnea, and caused a large number of chickens to die, causing serious economic losses. After epidemiological investigations, clinical observations, pathological necropsy and pathogen isolation and identification, the diagnosis was Pasteurellosis. The diagnosis and treatment are reported as follows:
I. Epidemiology
1. More than 4,300 chickens coexisted in two fields, and the incidence was 45-55 days old. No disease was found in the surrounding laying hens. 350 deaths occurred on the second day of illness, and the number of deaths reached 855 on the fifth day. The mortality rate was about 20%.
2. The breeding density of chicken farms is obviously large and the chickens are crowded. The sheds were built using unbuilt homes, with small venues, poor ventilation, strong ammonia odors, high humidity, high temperatures, and poor sanitation.
Second, the clinical symptoms of a short duration of no obvious symptoms of sudden death. Some chickens were only restless and died after licking several times in the chicken house. The chickens with slightly longer duration showed signs of wilting, were left alone, did not like activities, often closed their eyes and slept, and some sick chickens buried their heads in their wings. The feathers are loose and the wings are hanging down. Some showed breathing in the neck and the crown was dark black. Drain excreted grayish or greenish watery samples and contaminate the anus. The diseased chicken often makes harsh screams. The body temperature reaches 43°C-44°C, and most of the abdomen swells. Finally, it coma and paralysis and die.
Third, pathological anatomy The author examined 13 dead chickens, the appearance of thin, dirty around the anus. Three of them had no obvious lesions, only a small amount of effusion was found in the pericardium, and there was a small bleeding point in the epicardium. The remaining 10 necropsy patients had small bleeding points in the peritoneum, pericardial effusions, necrotic spots and bleeding spots on the surface of the liver, splenomegaly, and bleeding in the lungs. The small intestine flatulence, and there are different degrees of congestion and hemorrhage, intestinal mucous pink surface, especially in the duodenum is more serious.
Fourth, prevention and summary
1. Immediately after the outbreak, the chicken farm was sealed off and the chicken house and surrounding environment and utensils were diluted with 10% fresh milk of lime for disinfection. The diseased chickens were segregated and chickens that did not show symptoms were injected with birds anti-serum.
2. For diseased chickens, according to the size of the chicken, 2-5 million IU of penicillin is injected intramuscularly twice a day. Another 0.5% sulfamethazine was fed in the feed and used for 3-4 days.
3, Chinese medicine "three yellow soup" addition and subtraction treatment. Coptis 150 grams, 200 grams of astragalus, 80 grams of rhubarb, 200 grams of gentian, 200 grams of Banlangen, 250 grams of silver flower leaves, 250 grams of Andrographis paniculata, add 5,500 ml of water, stir-fry until 350 ml, make a 10-fold dilution, give all Chickens were used for drinking for 1 day for 4 days.
4. After 1-2 days of treatment, the death of chickens was significantly reduced. The condition of 3-4 days was basically controlled and no death occurred after 7 days.
Fifth, experience
1. Pasteurellosis is an infectious disease with high morbidity, fast infection, and high mortality rate. Once it breaks out, it can cause major economic losses.
2. There are many similarities between the disease and Newcastle disease in clinical symptoms and pathological anatomy. It is easy to confuse. To diagnose this disease, we must take the smear microscopic examination of the disease, and conduct pathogen isolation and identification.
3, should strengthen the daily feeding and management. According to the current feeding conditions, the disease is less common in chicken farms. However, due to the use of unbuilt homes in the two chicken farms as chicken coops, poor environmental conditions are the cause of this disease. Therefore, attention should be paid to the cleanliness and hygiene of the chicken house and the surrounding environment. The bedding should be changed frequently. At the same time, attention should be paid to the temperature, humidity and ventilation of the chicken house, and the poultry house should be disinfected regularly.
4. Doing preventive work is an important measure to prevent the occurrence of this disease. The chickens can be injected prophylactically with aluminum hydroxide inactivated bacterins at 15-20 days of age to enhance the chicken's immunity. Once the disease occurs, blockade and isolation treatment should be performed immediately and the house and surrounding environment and utensils must be thoroughly disinfected.
Puning City, Guangdong Province Animal Husbandry and Fisheries Bureau Qin Yurong Chen Shaoguang


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