Prevention and treatment of Toxoplasma gondii

Toxoplasmosis is a zoonotic parasitic disease that can occur throughout the year and can occur in different species, age, and sex.

First, the clinical symptoms of pigs suffering from lack of energy, eating less, happy to drink, body temperature of 40-42 °C, sows miscarriage, stillbirth, difficulty breathing (abdominal breathing), standing instability, sometimes sitting in dogs, ears and nose Hair cyanosis, the lower limbs, the medial and abdomen appear purple spots and small bleeding points, ear wing or even necrosis, the final lying in the ground, breathing is extremely difficult, body temperature dropped and died. The majority of miscarried fetuses are fresh, and a few are feted.

Second, the necropsy showed that swine lymph nodes were swollen, gray and white, wet machine, especially in the groin lymph nodes. Chest, abdominal effusion, heart, liver, lung, kidney and spleen have white necrosis. Lung lung, edema, hyperemia, surface a little bit like bleeding. There are red bubbles in the trachea, spots of gastric bleeding, and ulcers.

Third, the indoor test to take the dead pig's lymph nodes and organs as a contact sheet, by Wright's staining, Toxoplasma gondii can be further confirmed. Therefore, when there is no laboratory condition on the production line, a professional organization should be asked to make a microscopic examination before the disease name and cause can be confirmed.

IV. Prevention and treatment In addition to regular cleaning and sanitation, regular sterilization is required. Cats and dogs must be banned on farms, and rodents and insects must be regularly removed for careful introduction. There are two measures of drug prevention to choose from. One is to use the compound diploxacin or compound sulfamethoxazole, one cycle (7 days) of prevention is performed every quarter, the concentration is 0.05%; the second is after the piglet is born, and the other is 5 ,15,30 days of each use of toxoplasmosis immunosuppressed inactivated vaccine 1,2,3 ml for the prevention of injection, while the prevention of swine fever must also be strictly in accordance with the provisions of three consecutive injections to prevent. If the above two methods are used together, the effect is better.

The treatment of suffering from pigs are: (1) Sulfamethoxazole 6-methoxypyrimidine injection, 0.3-0.7 ml per kilogram of body weight, once a day, once every 3 to 5 days. (2) In the case of large-area infection, the compound doxycycline or sulfamethoxy-6-methoxypyrimidine sodium powder and baking soda are used in time, and they can be used for 4 to 5 days. (3) In order to prevent complications, one or two kinds of drugs such as roxithromycin, doxycycline, ring-shaped sensor-induced divergence, good shuhu, amikacin, etc., can be used in combination with bowelrin and other main drug ingredients. clothes. (4) Severely ill pigs should respond to fever, infusion, and use antibiotics to prevent secondary infection. After the condition is controlled, treatment should continue for 1-2 days. In addition, sulfa drugs should be used early and adequate. (5) Toxoplasmosis immunosuppressive inactivated vaccine treatment, the dosage of 2 ml per 5 kg body weight, subcutaneous injection, once every 3 to 4 days. In order to prevent the occurrence of other pigs, each sow is also injected with 25-30 ml every other day for 5 consecutive days and the epidemic will soon subside. According to reports (in 2005, Shi Dongmei, etc.), the positive rate of swine toxoplasmosis in Henan Province (clinical infection serum and other tests) was 13.21%, and there was no significant difference in geographical distribution. The positive rate in the suburbs of Zhengzhou was high and could be controlled. Reference when referring. In addition, prevention and treatment of the disease should be mainly prevention, due to multiple infections or secondary infections in other epidemics at the time of onset, comprehensive measures can be adopted to achieve better control effects. At the same time, Toxoplasma gondii has no infection, and its clinical symptoms are similar to those of some pig epidemics. Therefore, attention should be paid to differential diagnosis.

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