Norfloxacin is a fluoroquinolone antibiotic drug. It is a broad-spectrum antibacterial drug developed in the 1980s. It has strong antibacterial activity, good tissue penetration, almost no cross-resistance, low toxicity, and few adverse reactions. . However, animal experiments have shown that it can affect cartilage growth in young animals. Recent studies have shown that this type of drug can make the human bone callus ossification in advance.
Bone ridge line is the growth and development point of human bones, and it grows on both ends of the long bones of the limbs. Before 12 to 15 years of age, children’s bone ridge line cells are very active, so that children keep growing. If children in this period apply fluoroquinolones such as norfloxacin, the ossification line of some children will be prematurely ossified and affect children's growth.
Therefore, children should not take norfloxacin and other fluoroquinolones, and pregnant women and breastfeeding women should not be used, so as not to affect the normal growth and development of infants and young children through the maternal.
Bone ridge line is the growth and development point of human bones, and it grows on both ends of the long bones of the limbs. Before 12 to 15 years of age, children’s bone ridge line cells are very active, so that children keep growing. If children in this period apply fluoroquinolones such as norfloxacin, the ossification line of some children will be prematurely ossified and affect children's growth.
Therefore, children should not take norfloxacin and other fluoroquinolones, and pregnant women and breastfeeding women should not be used, so as not to affect the normal growth and development of infants and young children through the maternal.