Model NO.: CAS; 630-56-8 Hydroxyprogesterone Caproate
Product Name: Hydroxyprogesterone Caproate
CAS Register Number: 630-56-8
Molecular Formula: C27h40o4
Molecular Weight: 428.62
Appearance: White or Almost White Crystalline Powder
Assay: 98%
Trademark: SMQ
Transport Package: Disguise Package
Specification: SGS
Origin: Shenzhen
HS Code: 235532699
Progesterone Hormones 17α-Hydroxyprogesterone Caproate PowderÂ
Quick Detail:
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Product name | 17α-Hydroxyprogesterone caproate |
Other name | Hydroxyprogesterone caproate;17alpha-Hydroxyprogesterone caproate |
CAS register number | 630-56-8 |
Molecular formula | C27H40O4 |
Molecular weight | 428.62 |
Appearance | White or almost white crystalline powder |
Molecular structure |  |
Assay | 98% |
COA:
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Prodcut Name: Hydroxyprogesterone Caproate | ||
Standard:USP31 | ||
 |  |  |
Items | Standard | Resutls |
Description | White or almost white crystalline powder, odorless | Conforms |
Solubility | insoluble in water, solube in ether, slightly soluble in benzene | Conforms |
Specific Optical Rotation |  +58°---+64° (1% chloroform Solution) |  60.3° |
Melting Point | about 120 -124 ºC | 123ºC |
Water |  ≤0.1% | 0.05% |
Free N-Caproic Acid |  ≤0.58% | 0.20% |
Ordinary Impurities |  ≤2.0% | conforms |
Residual Solvents | Methanol ≤ 3000PPM | 1280PPM |
Ethanol≤5000PPM | 1500PPM | |
Dichloromethane ≤ 600PPM | 80PPM | |
Assay | 97.0%--103.0% | 99.30% |
Conclusion | Conforms to USP31 | Â |
Description;
To create a standardized formulation of 17P, the FDA approved Makena (KV Pharmaceutical Company), an orphan drug, on February 4, 2011. The approval was based on the premise that because 17P is a sterile injectable drug, a product approved according to FDA guidelines would provide "greater assurance of safety."10 Makena was approved via an accelerated approval process based on improvement in the proportion of women who delivered after 37 weeks of gestation. No controlled trials have demonstrated a direct clinical benefit of Makena, such as improvements in neonatal mortality and morbidity.
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The approved dosage of Makena is 250 mg (1 mL) weekly via IM injection, initiated at between 16 and 20 weeks of gestation and continued until week 37 or delivery, whichever occurs firs
Application;
Hydroxyprogesterone caproate injection is a man-made hormone of progestin. It is used in pregnant women to help lower the risk of giving birth too early ,This medicine is given only to pregnant women who are pregnant with one baby and who have had a preterm delivery of one baby in the past
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